Dr. Peter Attia: Supplements for Longevity & Their Efficacy
from Huberman Lab
by Scicomm Media
Published: Mon Jul 29 2024
Show Notes
In this episode, my guest is Dr. Peter Attia, M.D., a Stanford and Johns Hopkins School of Medicine-trained physician expert in improving human healthspan and lifespan. Dr. Attia is also the host of The Drive podcast and author of the best-selling book Outlive.
We discuss the NAD pathway in human cells and its possible links to aging and health. We evaluate how supplementation can augment molecules in the NAD pathway; we compare NAD, NMN, and NR, different routes of administration, their safety, and bioavailability. Then, we discuss the broader research and clinical literature on longevity to decide if supplementation with NAD, NR, NMN, rapamycin, or resveratrol can indeed extend lifespan.
Finally, we each describe our supplement regimens and compare the role of supplementation to behaviors such as sleep, nutrition, and exercise for longevity. We also discuss whether tests of biological age are true indicators of aging and whether normal radiation levels increase cancer risk.
Listeners of this episode will learn if supplements purported to improve lifespan show any efficacy and the behaviors and other factors that can prevent disease and extend lifespan.
Access the full show notes for this episode at hubermanlab.com.
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Timestamps
Dr. Peter Attia, NAD Pathway
Sponsors: LMNT, Levels & Eight Sleep
Categories of Longevity Approaches
Peter’s Supplements; Rapamycin & Research Data
NAD Pathway: Energy & DNA Repair; Knock-Out & Knock-In, Klotho
Sponsor: AG1
Yeast, Sirtuins, Caloric Restriction & Lifespan
Sirtuins, Transgenic Mice, Gender & Lifespan
DNA Repair, Sirtuins, Cancer; Resveratrol
Perform with Dr. Andy Galpin Podcast
NAD & NADH, Reactive Oxygen Species (ROS), Mitochondrial Health
NAD vs NR vs NMN Supplementation; IV & Oral Routes
NR vs. NMN, Doses, Side Effects; Interventions Testing Program
Fatty Liver Disease & NR; NMN & Glucose; Clinical Significance
Safety & FDA, NMN & NR Supplementation; Skin Cancer Benefits
Longevity, NR & NMN Supplementation, Inflammation
Rapamycin & Immune Function
Biological Aging Tests, Chronologic & Biologic Age; Vigor
Radiation & Cancer Risk
Tool: Self-Care in 50s-70s & Aging; Energy Decline
Tool: Exercise Timing & Energy Levels
Peter’s Supplements
Andrew’s Supplements
Tool: Supplement Use vs. Critical Behaviors; Titanic Analogy
NAD Pathway Supplementation for Longevity?
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